Antioxidant activity and chemical composition of extract from Myxopyrum smilacifolium trunk
Vol. 132 No. 1A (2023), Original Article
Vol. 132 No. 1A (2023)

Antioxidant activity and chemical composition of extract from Myxopyrum smilacifolium trunk

Original Article
https://doi.org/10.26459/hueunijns.v132i1A.7107
Published 2023-03-31
Le Trung Hieu*
Faculty of Chemistry, University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Vietnam
Nguyen Minh Nhung
Center for Measurement, Testing and Scientific Information, Thua Thien Hue Department of Science
Le Lam Son
Faculty of Chemistry, University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Vietnam
Nguyen Quang Man
University of Medicine and Pharmacy, Hue University, 6 Ngo Quyen St., Hue, Vietnam
Ho Xuan Anh Vu
Faculty of Chemistry, University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Vietnam
Tran Thanh Minh
Faculty of Chemistry, University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Vietnam
Nguyen Viet Thang
University of Medicine and Pharmacy, Hue University, 6 Ngo Quyen St., Hue, Vietnam
Nguyen Thi Nhu
Faculty of Chemistry, University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Vietnam
Tran Thi Van Thi
Faculty of Chemistry, University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Vietnam
PDF (Vietnamese)

Keywords

Sâm đá
chống oxy hoá
tổng các hợp chất phenol
tổng flavonoid
triterpenoid Myxopyrum smilacifolium
antioxidant activity
total phenolics
total flavonoid
triterpenoid

How to Cite

1.
Hiếu LT, Nguyễn Minh N, Lê Lâm S, Nguyễn Quang M, Hồ Xuân Anh V, Trần Thanh M, Nguyễn Việt T, Nguyễn Thị N, Trần Thị Văn T. Antioxidant activity and chemical composition of extract from Myxopyrum smilacifolium trunk. hueuni-jns [Internet]. 2023Mar.31 [cited 2024Nov.14];132(1A):139-47. Available from: http://222.255.146.83/index.php/hujos-ns/article/view/7107
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Abstract

Myxopyrum smilacifolium is an infused herb commonly used in folk remedies in Vietnam and other countries worldwide to treat nervous disorders, rheumatism, and bronchitis. The antioxidant potential of the ethanol extract was evaluated through DPPH and ABTS radical scavenging and the total antioxidant capacity method. The results show that the extract possesses high antioxidant activity, with a low IC50 value (IC50 = 42.23 and 46.57 μg·mL–1 for DPPH and ABTS radical scavenging capacity), and the total antioxidant capacity was 207.28 ± 8.43 mg GA·g–1. The chemical composition of Myxopyrum smilacifolium trunk extract, namely the total phenolics, total flavonoid, polysaccharides, and triterpenoid, was examined by using the colourimetric method. Their quantities are equivalent to 149.12 ± 1.36 mg GA·g–1 and 91.39 ± 1.33 mg QE·g–1, 5.12 ± 0.07%, and 35.22 ± 0.81 mg oleanolic acid·g–1, respectively. Specifically, the total triterpenoid content of Myxopyrum smilacifolium trunk was reported for the first time.

https://doi.org/10.26459/hueunijns.v132i1A.7107
PDF (Vietnamese)

References

  1. Praveen R, Nair AS. Preliminary phytochemical screening of root extracts of Myxopyrum smilacifolium Blume. Asian Journal of Biomedical and Pharmaceutical Sciences. 2014;4(38):41-45.
  2. Siju EN, Samu J, Minil M, and Rajalakshmi GR. Antioxidant activity of Myxopyrum Smilacifolium Blume. Asian Journal of Pharmaceutical and Clinical Research. 2015;8(3):119-121.
  3. Hộ PH. Cây cỏ Việt Nam Quyển II. Hà Nội: Nxb Trẻ. 2000; 889 p.
  4. Chi VV. Từ điển Cây thuốc Việt Nam. Hà Nội: Nxb Y học; 2012. 369 p.
  5. Praveen R, Nair AS. Antioxidant pontential of methanolic extract of root, callus and fruit extracts of Myxopyrum smilacifolium Blume. International Journal of Biological & Pharmaceutical Research. 2015;6(1):51-55.
  6. Rani TS, Gopal V, Lakshmi SS. Chitra K. In vitro anti-oxidant activity of Myxopyrum serratulum A.W Hill. International Journal of Biological & Pharmaceutical Research. 2013;5(4):545-546.
  7. Gopalakrishnan S, Rajameena R, Vadivel E. Antimicrobial activity of the leaves of Myxopyrum serratulum AW Hill. International Journal of Biological & Pharmaceutical Research. 2012;4:31-34.
  8. Rajalakshmi K, Mohan V. Antiinflammatory activity of stem and leaf of Myxopyrum serratulum AW Hill (Oleaceae). International Journal of Current Pharmaceutical Review and Research. 2016;7(4):190-192.
  9. Maruthamuthu V, Kandasamy R. Bronchodilatory effect of Myxopyrum serratulum in animal model. Bangladesh Journal of Pharmacology. 2017;12(1):84-90.
  10. Gopalakrishnan S, Rajameena R. Wound healing activity of the ethanolic of Myxopyrum serratulum AW Hills in rats. International Journal of Biological & Pharmaceutical Research. 2013;27:143-147.
  11. Praveen R, Ashalatha S. Study on cytotoxic effect of root and callus extracts of Myxopyrum smilacifolium Blume. International Journal of Biological & Pharmaceutical Research. 2015;7:345-348.
  12. Jolly S, Siju E, Minil M, Rajalakshmi G. In vitro anti-inflammatory activity of Myxopyrum smilacifolium Blume (Oleaceae). World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS). 2014;3(6):1822-1828.
  13. Peeriga R, Bonnth CK. Pharmacognostical Investigation and Preliminary Phytochemical Screening of Leaves of Myxopyrum Smilacifolium B. Pharmacognosy Journal. 2016;8(2):159-164.
  14. Damaso P, Reagan JI-u, Thu HLT, Le TT, Hong SL, et al. Nghiên cứu quy trình tách chiết polysaccaride tổng từ thân cây Sâm xuyên đá (Myxopyrum smilacifolium wall. blume) và đánh giá hoạt tính chống oxy hóa. Scientific Journal of Tan Trao university. 2020;6(17):36-41.
  15. Vuong NQ, Van CV, Hue NT, Hang PT, et al. Chemical constituents from the roots of Myxopyrum smilacifolium. Vietnam Journal of Science and Technology. 2021;59(4):498-506.
  16. Nair VD, et al. Studies on methanolic extract of Rauvolfia species from Southern Western Ghats of India–In vitro antioxidant properties, characterisation of nutrients and phytochemicals. Industrial Crops and Products. 2012;39:17-25.
  17. Prieto P, et al. Spectrophotometric quantitation of antioxidant capacity through the formation of a phosphomolybdenum complex: specific application to the determination of vitamin E. Analytical biochemistry. 1999;269(2):337-341.
  18. Wong SP, Leong LP, and Koh JHW. Antioxidant activities of aqueous extracts of selected plants. Food chemistry. 2006;99(4):775-783.
  19. Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radical Biology and Medicine. 1999;26(9):1231-7.
  20. Hieu TL, Thi TVT, Son LL, Nhung MN, Diep TNH, Mechler A, et al. Phenolic Contents and Antioxidant Activity of Helicteres Hirsuta Extracts. Letters in Organic Chemistry. 2021;18(2):128-33.
  21. Gan RY, Xu XR, Song FL, Kuang L, Li HB. Antioxidant activity and total phenolic content of medicinal plants associated with prevention and treatment of cardiovascular and cerebrovascular diseases. Journal of Medicinal Plants Research. 2010;4(22):2438-2444.
  22. Ribarova F, Atanassova M. Total phenolics and flavonoids in Bulgarian fruits and vegetables. Journal of the university of chemical technology and metallurgy. 2005;40(3):255-260.
  23. Hieu LT, Son LL, Nguyet NT, Nhung NM, Vu HXA, Man NQ, et al. In vitro antioxidant activity and Content of compounds from Curculigo orchioides rhizome. Hue University Journal of Science: Natural Science. 2020;129(1B):71-77.
  24. Dubois M, Gilles K, Hamilton J, Rebers P, Smith F. A colorimetric method for the determination of sugars. Nature. 1951;167.
  25. Jayaprakasha G, Selvi T, Sakariah K. Antibacterial and antioxidant activities of grape (Vitis vinifera) seed extracts. Food research international. 2003;36(2):117-22.
  26. Dasgupta N, De B. Antioxidant activity of Piper betle L. leaf extract in vitro. Food chemistry. 2004;88(2):219-224.
  27. Al-Laith AA, Alkhuzai J, Freije A. Assessment of antioxidant activities of three wild medicinal plants from Bahrain. Arabian Journal of Chemistry. 2019;12(8):2365-2371.
  28. Noreen H, Semmar N, Farman M, McCullagh JS. Measurement of total phenolic content and antioxidant activity of aerial parts of medicinal plant Coronopus didymus. Asian Pacific journal of tropical medicine. 2017;10(8):792-801.
  29. Adewusi EA, Moodley N, Steenkamp V. Antioxidant and acetylcholinesterase inhibitory activity of selected southern African medicinal plants. South African Journal of Botany. 2011;77(3):638-44.
  30. Guha G, et al. The antioxidant and DNA protection potential of Indian tribal medicinal plants. Turkish Journal of Biology. 2011;35(2):233-242.
  31. Coulibaly AY, Hashim R, Sulaiman SF, Sulaiman O, Ang LZP, Ooi KL. Bioprospecting medicinal plants for antioxidant components. Asian Pacific journal of tropical medicine. 2014;7:S553-S559.
  32. Kim MH, Kim JM, Yoon KY. Effects of blanching on antioxidant activity and total phenolic content according to type of medicinal plants. Food Science and Biotechnology. 2013;22:817-823.
  33. Banothu V, Adepally U, Lingam J. In vitro total phenolics, flavonoids contents, antioxidant and antimicrobial activites of various solvent extracts from the medicinal plant Physalis minima Linn. International Journal of Pharmacy and Pharmaceutical Sciences. 2017;9(3):192-198.
  34. Karimi E, Mehrabanjoubani P, Homayouni-Tabrizi M, Abdolzadeh A, Soltani M. Phytochemical evaluation, antioxidant properties and antibacterial activity of Iranian medicinal herb Galanthus transcaucasicus Fomin. Journal of Food Measurement and Characterization. 2018;12:433-440.
  35. Nguyen VT, Nguyen MT, Nguyen NQ, Truc TT. Phytochemical screening, antioxidant activities, total phenolics and flavonoids content of leaves from Persicaria odorata Polygonaceae. IOP Conference Series: Materials Science and Engineering. 2020;1-6.
  36. Tang Z, Wang Y, Yang J, Xiao Y, Cai Y, Wan Y, et al. Isolation and identification of flavonoid-producing endophytic fungi from medicinal plant Conyza blinii H. Lév that exhibit higher antioxidant and antibacterial activities. Peer J. 2020;8:e.8978.
  37. Cai Y, Luo Q, Sun M, Corke H. Antioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer. Life Sciences. 2004;74(17):2157-84.
  38. Fu L, Xu B-T, Gan R-Y, Zhang Y, Xu X-R, Xia E-Q, et al. Total Phenolic Contents and Antioxidant Capacities of Herbal and Tea Infusions. 2011;12(4):2112-24.
  39. Rani TS, Gopal V, Seethalakshmi S, Chitra K. Quantification and screening of phytoconstituents in selected medicinal plant. Research Journal of Pharmacy and Technology. 2013;6(11):1235-1236.
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